Retatrutide ZPHC 10 mg – Pharma Grade Quality
Active Substance: Retatrutide
Brand: ZPHC
Pack: 10 mg vial
Shipping: Only USA Domestic
Retatrutide ZPHC – Triple-Receptor Agonist for Advanced Fat Loss – 10 mg vial
This is the next evolution past semaglutide and tirzepatide. Retatrutide ZPHC hits three different receptors at once—GIP, GLP-1, and glucagon—which is why it’s showing better fat loss results than anything else in clinical trials right now. ZPHC’s putting out pharmaceutical-grade product while most people are still trying to figure out how to pronounce it.
What makes it different:
Semaglutide (Ozempic, Wegovy) only hits GLP-1. Tirzepatide (Mounjaro, Zepbound) hits GLP-1 and GIP. Retatrutide ZPHC hits all three receptors, including glucagon, which directly ramps up your metabolic rate and fat oxidation. You’re not just eating less—your body’s actively burning stored fat faster.
How it actually works:
The GLP-1 part crushes your appetite and slows digestion. You just don’t think about food as much, and when you do eat, you get full stupid fast. GIP improves insulin sensitivity and helps with nutrient partitioning. The glucagon receptor activation is where the magic happens—it signals your body to break down fat stores for energy while preserving muscle tissue.
Clinical trial subjects dropped serious weight. We’re talking 24-25% total body weight over 48 weeks. That’s not “I lost ten pounds” weight loss—that’s complete body recomposition. And they kept lean mass better than with other GLP-1s.
Real talk on appetite suppression:
It’s strong. Like, you might forget to eat strong. First few weeks you need to actually set reminders to get your protein in because hunger signals basically disappear. Some people get mild nausea early on, usually passes after the first week or two. Start low, ramp up slow, and you’ll avoid most of the rough stuff.
Dosing protocol that works:
This is where people screw up. You can’t just blast 10 mg your first shot—you’ll be miserable.
Week 1-2: 0.5-1 mg once weekly. Get your body used to it. You’ll notice appetite dropping but it won’t wreck you.
Week 3-4: 2-2.5 mg weekly. Now you’re in effective fat loss range. Food noise pretty much gone.
Week 5-8: 4-6 mg weekly. This is where most people sit for extended cuts. Aggressive fat loss without feeling like death.
Week 9+: Some push to 8-12 mg weekly for maximum effect. Not everyone needs this much. Listen to your body.
Each 10 mg vial gives you multiple doses depending on where you are in your ramp-up. Typical protocol runs 12-16 weeks, sometimes longer for significant weight loss goals.
Reconstitution is standard:
Add 2 ml bacteriostatic water to your 10 mg vial. That gives you 5 mg per ml, makes dosing math easy. If you’re running 2 mg weekly, you’re drawing 0.4 ml. Keep it simple.
Injection timing:
Once weekly, same day each week. Doesn’t matter what time—morning, night, whenever. Sub-Q injection, usually belly fat. Insulin syringe makes it painless. Whole process takes thirty seconds.
What to expect week by week:
First week: Appetite starts dropping. Might feel slightly off, maybe some mild nausea. Nothing crazy.
Week 2-3: Food just doesn’t hit the same. You’re eating because you know you should, not because you’re hungry. Energy stays solid though.
Week 4-6: Scale’s moving consistently. Half pound to pound per week depending on your deficit. Clothes fitting different. People start noticing.
Week 8-12: Body comp changes are obvious. Leaner face, tighter waist, more definition. If you’re training and eating enough protein, you’re keeping your muscle.
Week 12+: You’re at your goal weight or damn close. Time to think about maintenance dose or transitioning off.
Best practices while running it:
Protein is non-negotiable. You’re eating way less food, so every meal needs to count. Shoot for 1g per pound of goal body weight minimum. Protein shakes become your friend because drinking 40g of protein is easier than forcing down a chicken breast when you’re not hungry.
Train heavy. Don’t fall into the cardio trap. Keep lifting hard to signal your body to hold onto muscle. You’re in a deficit, you don’t need more reasons to lose strength.
Hydrate constantly. Easy to get dehydrated when you’re not eating much. Two gallons minimum. Electrolytes help.
Track your food. When appetite’s gone, it’s real easy to under-eat protein and over-cut calories. Both will cost you muscle. Use an app, weigh your food for a few weeks until you dial it in.
Possible side effects to watch:
Most common is nausea and maybe some heartburn first couple weeks. Usually fades fast. Some people get constipated because they’re eating less—fiber and water fix that. Fatigue can hit if you cut calories too hard—don’t be stupid, keep your deficit reasonable.
Rare but serious: If you get severe stomach pain, persistent vomiting, or feel your heart racing weird, stop and see a doctor. Pancreatitis risk exists with all GLP-1 drugs, though it’s pretty rare.
Who shouldn’t use this:
Personal or family history of thyroid cancer (specifically medullary). History of pancreatitis. Type 1 diabetics need doctor supervision. If you’re already lean (sub 12% for guys, sub 20% for women), you probably don’t need this—diet and cardio will get you there.
Stacking options:
Works solo just fine. Some guys add it to their cruise dose of test to lean out between blasts. Pairs well with low-dose anavar or primo if you want to hold max muscle during aggressive cuts. Don’t stack with other GLP-1s—pointless and asking for side effects.
Can run alongside moderate cardio and lifting. Don’t need to do hours of cardio—the fat loss happens from the metabolic boost and calorie deficit.
Coming off protocol:
Don’t just stop cold turkey after months of use. Taper down over 2-3 weeks. Your appetite will come back—be ready for it. Have your maintenance diet planned out before you finish your last vial or you’ll rebound fast.
Most people keep 80-90% of their weight loss off if they transition smart. The ones who gain it all back are the ones who immediately start eating like they did before.
Storage and handling:
Unopened vials stay in the fridge (not freezer). Once you add bac water, keep it refrigerated and use within 28 days. These peptides are stable but don’t test it by leaving them out.
Pharmaceutical quality confirmed:
ZPHC runs full purity testing on every batch. You’re getting ≥98% pure retatrutide, tested for endotoxins and contaminants. Each vial includes verification code you can scratch off and check on their site. Takes one minute to confirm it’s legit.
Cold-chain shipping locked down:
Ships in medical-grade insulated packaging, temperature controlled 2-8°C the whole way. Includes temp indicator so you know your peptide stayed cold from warehouse to your door. This isn’t some sketchy operation—this is pharma protocol.
Real results from real people:
Guy at 240 lbs running 4 mg weekly dropped to 195 in four months while keeping his lifts nearly identical. Woman at 180 hit 145 in five months, went from size 12 to size 4. These aren’t freak results—this is what happens when you run the protocol right and don’t sabotage yourself.
Bottom line:
If you’ve got serious fat to lose and diet alone isn’t cutting it anymore, Retatrutide ZPHC is the strongest tool available right now. It’s not magic—you still need to eat right and train—but it makes the whole process way less miserable. Hunger’s gone, energy stays decent, and the fat comes off consistently.







